Valentine's Special

Wrinkle Smoothing in Mishawaka

BOTOX, Dysport and Xeomin Injectables

Botulinum Toxins are commonly called BOTOX® which is a trademarked name from Allergan, though other brand names include Dysport® and Xeomin®. 

BOTOX injections are a prescription medicine derived from a powerful natural protein. They are designed to block muscle movement at the injection site for 3 to 4 months.

Although botulinum toxins do not erase etched-in lines, over time they can prevent the line from deepening. When injected, the substance works to “weaken” the muscles linked to common facial expressions, giving you a softer, younger and more radiant look.

At our Mishawaka clinic, BOTOX injections are especially effective at temporarily improving the look of stubborn forehead furrows, wrinkles between the eyes, and “crow’s feet” areas around the upper third of the face. These wrinkle smoothing treatments have helped clients in Elkhart, South Bend, and areas across Indiana.

BOTOX also works well when used in conjunction with dermal fillers, such as Restylane®, Perlane®, JUVÉDERM® XC and Radiesse®, all of which help smooth lines and folds by adding volume beneath the skin’s surface.


Xeomin®, BOTOX® Cosmetic and Dysport® are injections that temporarily improve the look of moderate to severe frown lines without changing the look of your face.

  • Improves gummy smile
  • Soften furrow lines around eyes and forehead
  • Lifts turned down corners of the mouth
  • Softens lines between eyebrows
  • Softens line across forehead
  • Softens bunny lines on nose

Xeomin®, BOTOX® Cosmetic and Dysport® are made of purified protein that is safe and FDA approved. Injections of appropriate doses, of Xeomin®, BOTOX® Cosmetic or Dysport® weaken muscles (which contract with expression creating wrinkles and creases) to decrease wrinkles and reduce and eliminate lines.

Expressions are still possible! Results take up to 10 days to occur and last 4 months on average. The key is to be treated every 4 months so wrinkles occur less because of decreased muscle movement. In the long run, this will cost less and provide the best results.


It is made from the same active ingredient as BOTOX® Cosmetic, botulinum toxin type A. It works by relaxing the facial muscles, thereby reducing and smoothing away frown-lines and wrinkles.

It also works well with dermal fillers such as Restylane®, Perlane®, and Radiesse®, which erase lines and folds by adding volume beneath the skin’s surface. Initial reports suggest that Dysport® may act quicker than BOTOX® Cosmetic. BOTOX® takes three to five days to work, while Dysport seems to work within one to two days.

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Meet the Doctors
Dr. Downs
Dr. Downs

Ronald K. Downs, M.D., F.A.C.S. founded The Centre, P.C. in Elkhart, Indiana in 1992. He is an active member in the American Society of Plastic Surgeons. Dr. Downs is also a member of The American Society for Aesthetic Plastic Surgery, The American Medical Association, The Ohio Valley Plastic Surgery Society, The Rush Surgical Society, and The Indiana State Medical Association where he serves on the board of directors and has served as the president from 2003 to 2004.

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Dr. Downs
Dr. Macias

Dr. Macias completed her plastic and reconstructive surgery residency training at Spectrum Health/Michigan State University in Grand Rapids, Michigan. She is Board Certified with the American Board of Plastic Surgery.

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Dr. Viscardi
Dr. Viscardi

Patrick J. Viscardi, M.D. has been part of the surgical team at The Centre, P.C. since 1998. Dr. Viscardi graduated from Dartmouth College in Hanover, New Hampshire, as a summa cum laude. He received his Doctor of Medicine Degree from the University of Rochester in New York. Dr. Viscardi completed his internship and general surgery residency at the University of Louisville, where he served as chief resident from 1994 to 1995.

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